Search on: DUAL OXIDASES 
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Descriptor English:   Dual Oxidases 
Descriptor Spanish:   Oxidasas Duales 
Descriptor Portuguese:   Oxidases Duais 
Synonyms English:   DUOX1
DUOX2
Dual Oxidase 1
Dual Oxidase 2
Duox Proteins
NADPH Thyroid Oxidase 2
Thyroid Oxidase 2
Oxidase 1, Dual
Oxidase 2, Dual
Oxidase 2, Thyroid
Oxidases, Dual
Proteins, Duox  
Tree Number:   D08.811.682.608.575.500
D12.776.331.894.500
D12.776.543.653.500
Definition English:   NADPH oxidases that contain two additional EF HAND MOTIFS and an N-terminal PEROXIDASE domain. They are expressed by THYROCYTES and EPITHELIAL CELLS of the kidney, liver, trachea, lung, and glandular tissues such as the testis, pancreas, and prostate. They are critical for the activity of THYROID PEROXIDASE and play a role in the production of thyroid hormones; they may also have antimicrobial activity through the generation of REACTIVE OXYGEN SPECIES. 
History Note English:   2018 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   57022 
Unique Identifier:   D000074623 

Occurrence in VHL:
 

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